Thermoelectric conversion is a kind of technology of heat-to-electricity based on Seebeck and Peltier effect. It includes two types of applications: Thermoelectric Cooling and Thermoelectric Power Generation. It possesses compact structure, no noise, no wear, and no leakage characteristics. Focusing on　thermoelectric cooling application research, researchers from NIMTE studied bismuth-telluride-based alloys, analysed optimal design for chemical compositions and new preparation technologies, under the room temperature, the value of ZT of the bismuth-telluride-based sintered materials they developed can reach to 1.2, which brought about their mechanical properties have been improved greatly, thus it made the utilization of type of N and P soar to 51.3％and 50.7％ respectively, 10％ higher than FZ materials; for high-strength suppression materials. the maximum temperature difference of prepared devices is 67.4℃. By cooperating with industries, the result has made significant economic benefits. Moreover, we have also made some progress in thermoelectric power generation, mixing Te into the ZnSb matrix material resulted in the enhancement of the value of ZT from 0.8 to 1.0.