(1) Super-resolution microscopy and its applications in cell biology and pathology;
(2) High throughput 3D imaging instrumentation and its applications in drug screening;
(3) Intelligent microscopy based on optical computation and optical neuron networks.

2023/10-present：Ningbo Institute of Materials Technology and Engineering, CAS, Research Professor;
2013/07-2023/09: Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Research Professor;
2012/11-2013/06: Department of Electrical Engineering, University of Notre Dame, Research Assistant;
2009/11-2012/10: Department of Physics and Astronomy, Iowa State University, Research Assistant;
2006/07-2009-08: Department of Physics, University of Konstanz, Research Assistant;
2004/08-2006/07: Institute of Biophysics, Chinese Academy of Sciences, Research Assistant

1.Yifan Zhang, Chong Chen, Yao Tan, Yanjie Lu,Xuefei Chen, Guang Yang, and Hui Li*，Direct Blood Flow Velocity Measurements of Zebrafish Cerebral Vessels with a Dual-mode Light-Sheet Microscope，Biomedical Optics Express，（7）2025，2073-2583
2.Yujun Tang,Gang Wen*, Linbo Wang, Hui Li*,Quantitative evaluation and refinement of super-resolution image intensity fidelity for structured illumination microscopy ,Journal of Innovative Optical Health Sciences，5（2024）,2450026
3.Xiaohu Chen , Lei Jin, Cong Chen , Simin Li, Jie Zhang, Pengjiu Zhao , Shoupeng Liu,Yong Liang, Xin Jin, Cheng-Wei Qiu*, and Hui Li*. Single-Wavelength Focusing Metalens for Multichannel Two-Photon Microscopy. IEEE Photonics Technology Letters, 35(2023), 1407-1410.
4.Xiaoyin Li, Cong Chen, Yinghui Guo*, Qiong He, Runzhe Zhang, Mingbo Pu, Xiaohu Chen, Xin Jin, Hui Li*, Xiangang Luo*. Monolithic Spiral Metalens for Ultrahigh-Capacity and Single-Shot Sorting of Full Angular Momentum State. Advanced Functional Materials, 2023, 2311286.
5.Gang Wen, Simin Li, Yong Liang, Linbo Wang, Jie Zhang, Xiaohu Chen, Xin Jin, Chong Chen, Yuguo Tang,* and Hui Li*. Spectrum-optimized direct image reconstruction of super-resolution structured illumination microscopy. PhotoniX, 4(2023), 19. IF: 19.8.
6.Yujun Tang, Gang Wen, Yong Liang, LinBo Wang, Jie Zhang, and Hui Li*. Keyframe-aided resolution enhancement network for dynamic super-resolution structured illumination microscopy. Optics Letters. 48(2023), 2949-2952.
7.Cong Chen, Xiaoyin Li, Gang Yang, Xiaohu Chen, Shoupeng Liu, Yinghui Guo* and Hui Li*. Computational hyperspectral devices based on quasi-random metasurface supercells. Nanoscale, 15(2023), 8854-8862. IF: 8.3.
8.Yue Xu, Chuanwen Guo, Xueyi Yang, Weihong Yuan, Xu Zhang, Yujie Sun, Gang Wen, Linbo Wang,Hui Li,* Chunyang Xiong * and Chun Yang*. Super-resolution traction force microscopy with enhanced tracer density enables capturing molecular scale traction. Biomaterials Science,11(2023), 1056-1065. IF: 7.59
9.Chong Chen, YuJun Tang, Yao Tan, LinBo Wang, and Hui Li*. Three-dimensional cerebral vasculature topological parameter extraction of transgenic zebrafish embryos with a filling-enhancement deep learning network. Biomedical Optics Express, 14(2023), 971. IF: 3.56
10.Guang Yang, Linbo Wang, Xiaofei Qin, Xiaohu Chen, Yong Liang, Xin Jin, Chong Chen, Wenjuan Zhang, Weijun Pan, Hui Li*. Heterogeneities of zebrafish vasculature development studied by a high throughput light-sheet flow imaging system. Biomedical Optics Express, 13(2022),2344. IF: 3.56
11.Jingyi Yin, Guang Yang, Xiaofei Qin, Hui Li, Linbo Wang. Optimized U-Net model for 3D light-sheet image segmentation of zebrafish trunk vessels. Biomedical Optics Express,13(2022), 2896. IF: 3.56
12.Changyuan Fan, Xuemeng Shi, Kaikai Zhao, Linbo Wang, Kun Shi, Yan-jun Liu, Hui Li, Baohua Ji, Yaming Jiu. Cell migration orchestrates migrasome formation by shaping retraction fibers. Journal of Cell Biology, 221(2022), 202109168. IF: 9.83
13.Cheng Zhu, Chong Chen, Jinsong Guo, Qun Wang, Junfeng Rao, Hui Li, Xiaodong Wu, Jie Zhuang. Cold atmospheric plasma inhibits vesicle transport of human osteosarcoma cells visualized by super-resolution fluorescence Microscopy. Plasma Processes and Polymers, 2022; e2100210. IF:3.87
14.Gang Wen, Simin Li, Linbo Wang, Xiaohu Chen, Zhenglong Sun, Yong Liang, Xin Jin, Yifan Xing, Yaming Jiu, Yuguo Tang*, Hui Li*. High-fidelity structured illumination microscopy by point-spread-function engineering. Light: Science & Applications, 10(2021), 70. IF: 20.2
15.Yong Liang, Xiaohu Chen, Zhenglong Sun, Gang Wen, Chong Chen, Xin Jin, Jie Zhang, Guang Yang, Jing Gao, Hui Li, Simin Li*. High dynamic range structured illumnination microscope based on multiple exposures. Frontiers in Physics, 9(2021), 648174. IF:3.78